lupus.bmj9h
Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus
Background SLE is a systemic autoimmune disease with a large number of common risk gene variants, but several rare gene ...
Chemistry World13h
First direct chemical synthesis of a gene over 1700 nucleotides long
Direct chemical synthesis has been adapted to make oligonucleotides of remarkable length, including an 800 nucleotide green fluorescent protein gene and a 1728 nucleotide bacteriophage DNA polymerase ...
Nature6y
Variation is the spice of life
The International SNP Map Working Group has compiled a map of 1.4 million single-nucleotide polymorphisms. What fraction of all human sequence variation is captured in this collection, and what ...
JSTOR Daily1y
Nucleotide exchange factor SIL1 promotes the progress of breast cancer cells via regulating the cell cycle and apoptosis
8. Bracher A and Verghese J. GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: nucleotide exchange factors for Hsp70 molecular chaperones. Subcell Biochem 2015; 78: 1–33. 9. Hetz C and Saxena ...
Nature1y
Capture Compounds for the functional isolation of nucleotide interacting proteins
Figure 1: Classification of captured proteins from HepG2 cell lysate using cAMP Capture Compounds, based on their biological process properties. Guanosine nucleotide binding proteins (G proteins ...