Bilirubin is a viscous, brownish-yellow substance that is a natural byproduct of liver processes like breaking down old red blood cells. Normally, it is excreted from the body without cause for ...

View Full Profile. Learn about our Editorial Policies. When bilirubin passes through the gut, it is either broken down by bacteria and expelled from the body or reabsorbed, where it accumulates.

But the biotech announced this morning that two unanticipated grade 3 events of elevated unconjugated bilirubin—a biomarker of liver injury—had been reported in the multiple ascending dose ...