Background: Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in ...

Being obese at the time of MGUS diagnosis was associated with a 27% increase in the risk of progression to MM.

SAN DIEGO -- The risk of progression from smoldering multiple myeloma to symptomatic disease ... uninvolved free light chain ratio ≥8 and 100, and BMPCs >50% but <60%. Patients were randomized ...

Black Americans have double the risk of developing multiple myeloma compared to white Americans and are diagnosed at younger ages.

A multiple myeloma diagnosis is a life event that can be overwhelming. Get trusted information for every step of your journey. Multiple myeloma can be tricky. That’s because it sometimes has no ...

It isn’t blood cancer in itself, but some people with MGUS will eventually develop multiple myeloma or other related blood cancers. MGUS comes in three types: IgM, non-IgM, and light chain.

Study reveals VLCFA metabolism as a key target in multiple myeloma, enhancing drug efficacy and overcoming resistance.

A common cause of this type of cardiac amyloidosis is having a diagnosis of certain blood cancers, like multiple myeloma.

A stem cell transplant can be a good treatment for multiple myeloma. A successful transplant gives someone with multiple myeloma new, healthy bone marrow. It replaces the bone marrow harmed by myeloma ...

We do not know what causes MGUS. There may be a link to autoimmune diseases, genetics, or environmental factors. Like multiple myeloma, MGUS starts in a type of white blood cell called plasma cells.

Before serum FLC assays became available, urine analysis was the preferred method for identifying monoclonal FLC production in routine haematological screens for multiple myeloma and other ...