Head coach Kyle Shanahan told reporters at a Monday press conference that running back Isaac Guerendo is going to miss will ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

It’s time for the San Francisco 49ers to reevaluate the running back position. The depth chart order behind Christian ...

San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

The San Francisco 49ers seem to be off to a rough start with two concerning training camp injuries revealed by Kyle Shanahan.

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Monday's practice—the team's first of the week as it ...

San Francisco 49ers running back Isaac Guerendo (shoulder) is expected to miss a couple of weeks, according to Matt Maiocco ...

Injuries forced running back Isaac Guerendo and fullback Kyle Juszczyk out of Saturday’s practice at 49ers training camp.

Discover the top breakout running backs for 2025 fantasy football drafts, including Jordan Mason, Isaac Guerendo, and Omarion ...

Stats and projections for Isaac Guerendo in fantasy football, including ADP, insights, and 2025 outlook, as the San Francisco ...

What’s changed: Healthy since early in the offseason, McCaffrey predictably earned raves for his spring work. Coach Kyle ...

Isaac Guerendo ’s mother, Jen, realized that early on. She remembers a family gathering at a park in southern Indiana during which the kids had a big race. Isaac was 5 or 6 at the time.