Lionel Messi is expected to play as Inter Miami faces Sporting San Miguelito in Panama City, Panama at 5 p.m. ET. Here's what you need to know.

The preseason match, which kicks off at 5 p.m., is the third in the club’s Americas Tour, which also includes a game against Olimpia in Honduras next Saturday. Miami won its first two preseason games in penalty kick shootouts against Mexican team Club America and Universitario of Peru.

After kicking off their preseason in Las Vegas with a 2-2 draw against Club America, Inter Miami will now travel to Peru where 80,000 fans are expected to be in attendance to see Lionel Messi, Luis Suarez,

Lionel Messi failed to score, but Inter Miami beat Universitario – Peruvian’s back-to-back champions – with a 5-4 edge in penalty kicks on Wednesday.

Lionel Messi is set to lose an Argentine teammate as part of Inter Miami's squad restructuring under head coach Javier Mascherano.

Inter Miami appointed one of Lionel Messi's most influential coaches as the new man overseeing sporting matters.

Lionel Messi is expected to play as Inter Miami faces Sporting San Miguelito in Panama City, Panama at 5 p.m. ET. Here's what you need to know.

Lionel Messi's bodyguard has done a terrific job protecting the football icon from excited fans during his time at Inter Miami. However, that didn't happen on Sunday night with Yassine Chueko unable to prevent one supporter from getting to the forward.

Inter Miami's club valuation rose 19 percent year-over-year as Lionel Messi continues to impact the league on and off the pitch.

Lionel Messi has appeared strong and in prime form in Inter Miami’s first two preseason games of the year. He's expected to play Sunday in Panama.