His contributions in this area also include the discovery of the function of biotin (vitamin H) as the prosthetic group of one of the active enzymes, and the identification of malonyl-CoA as the ...
coelicolor. The proteins have KR been purified. Crude cell free extracts containing the expressed proteins synthesise a range of compounds when supplemented with 14C-acetyl and malonyl-CoA. Assays are ...