The clinical name for Down syndrome is trisomy 21, a condition in which a person is born with an extra chromosome, causing mild to moderate cognitive disability, developmental delays and physical challenges.

"This is the first time I can pick a number that's not just close to my heart, but close to a lot of people's hearts," Jake Burger, a CBC graduate,

The new Rangers first baseman announced Friday that he will wear No. 21 to pay tribute to Penelope, who was born with Down Syndrome, and to raise awareness for the genetic condition.

The Texas Rangers player, 28, will wear number 21 for the 2025 season in honor of his daughter Penelope, who was born with Down syndrome, according to the Major Baseball League. The genetic condition, known as Trisomy 21, results in an extra copy of chromosome 21.

ARLINGTON, Texas - New Texas Rangers corner infielder Jake Burger picked his new jersey number to honor his daughter. Burger will wear the number 21 with the Rangers this season. Burger chose the number in honor of his daughter, Penelope, who was born with Down syndrome.

Jake Burger will wear No. 21 with the Texas Rangers, a number that has special significance for the first baseman’s family after his daughter was born with Down

Jake Burger will wear No. 21 after being acquired by the Texas Rangers. The number has special significance for his family after his daughter was born in October with Down syndrome.

Down Syndrome is also known as Trisomy 21, and Burger wants to raise awareness and contribute to research on the genetic condition.

ARLINGTON, Texas (AP) — Jake Burger will wear No. 21 with the Texas Rangers, a number that has special significance for the first baseman's family after his daughter was born with Down syndrome.

Steven Nelson says he was a lookout for a robbery that ended in a pastor’s death. He’s set to be killed by the state February 5.

Daily on Defense: 10,000 troops destined for border, Hegseth vote expected today, Houthis redesignated terrorists, Judges recoil at revisionist Jan. 6 history.

House G.O.P. Floats Medicaid Cuts and More to Finance Trump’s Huge Agenda President Trump wants a massive tax cut and immigration crackdown bill. Republicans must decide what to cut to help pay ...