A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called ...

A visual depiction of a frameshift mutation. What is a duplication mutation? In the case of a duplication mutation, a piece of DNA is (abnormally) copied. This might happen once or several times, and ...

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The ...

The frameshift mutation results in a premature stop codon (I390fs404X) that predicts a truncated protein of 404 amino acids, with a terminal sequence of 15 amino acids bearing no homology to the ...

In a paper published on aBIOTECH, the authors obtained viable knockout mutants with developmental defects by introducing frameshift mutations to C -terminus sequence of three essential protein kinase ...

Identification of a novel frameshift mutation in the SCNN1B causing Liddle syndrome. Science China Press. Journal Science Bulletin DOI 10.1016/j.scib.2023.02.006. Keywords / Life sciences ...

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not ...

It demonstrated impressive neoantigen-specific T cell responses in all evaluable participants, inducing durable and robust immune responses against frameshift peptide neoantigens. Lynch Syndrome is ...