Sickle Cell Disease is a complex and debilitating genetic blood disorder that primarily affects people of African, ...

AG10 for ATTR cardiomyopathy and ALXN2040 or PNH patients with extravascular haemolysis (EVH). “Alexion has established itself as a leader in complement biology, bringing life-changing benefits ...

which showed that crovalimab was as effective as Soliris at controlling the destruction of red blood cells (haemolysis) that characterises PNH, whilst also reducing the need for blood transfusions.

Smith, A. U., Lancet, ii, 910 (1950). Sloviter, H. A., Lancet, i, 823 (1951). Mollison, P. L., and Sloviter, H. A., Lancet, ii, 862 (1951).

OBJECTIVE To evaluate signs of haemolysis in babies of Rh-D negative mothers who underwent prophylaxis with anti-D immunoglobulin during pregnancy. DESIGN The following were evaluated in all babies of ...

While HS in this patient has been categorised as mild and is unlikely to require any intervention, the haemolysis is of clinical significance since it inadvertently delayed the diagnosis of diabetes.

CONCLUSIONS Anaemia in SLE usually takes the form of ACD and IDA, however autoimmune haemolysis is not uncommon. SLE patients with different causes of anaemia differ in regard to several immunological ...

The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood. However ...

The results of most clinical trials with the thistle (Silybum marianum) extract, silymarin, are difficult to interpret because of a variety of reasons: small sample size, variability in type and ...