1998). Interestingly, histone H1 is very important in stabilizing chromatin higher-order structures, and 30-nanometer fibers form most readily when H1 is present. Processes such as transcription ...
The linker histone H1 binds to the nucleosome core particle at the site where DNA enters and exits, and facilitates folding of the nucleosomes into a higher-order chromatin structure in eukaryotes.
Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...
Version of Record: This is the final version of the article. This study combines hESC engineering, differentiation, detailed gene expression, genome occupancy, and pathway modulation to elucidate the ...
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R-loops are three-stranded non-canonical nucleic acid structures composed of nascent RNA hybridized with the template DNA strand, leaving the non-template DNA strand displaced. These structures play ...
The membranes were blocked with Odyssey PBS Blocking Buffer (927-70001, LiCor) and incubated with primary antibodies phospho-histone H2A.X (Ser139; 20E3; 9718, Cell Signaling Technology; RRID: ...
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Department of Surgery, Division of Surgical Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States Center for Systems Immunology, University of Pittsburgh, Pittsburgh, ...
The Institute for Drug Research, The School of Pharmacy, The Faculty of Medicine, The Hebrew University, POB 12271, Jerusalem 9112001, Israel ...
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