Understanding the steps of meiosis is essential to learning how errors occur. Researchers' initial understanding of meiosis was based upon careful observations of chromosome behavior using light ...

In the United States, more than 11% of men under the age of 49 are infertile. While the causes are varied and range from ...

A genetic mutation in mice affects cells required for sexual reproduction and holds clues about male infertility that could pave the way for new treatments and male contraceptives, a Rutgers ...

During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together ...

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But ...

This sets up a new structure that cements the cell's future fate as a sperm cell. The companion paper shows that well before ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands ...

Two new studies uncover how DNA folding controls sperm cell development. Researchers identified proteins that rearrange ...

The companion paper shows that well before the germ cells enter meiosis, CTCF and other proteins bookmark thousands of locations in the genome. This paper was led by postdoctoral fellow Chongil Yi ...