Mitochondria generate ATP through oxidative phosphorylation, and also have a central role in apoptosis. A new study reveals that in drastic contrast to other cancer types, translocation renal cell ...

Metabolic alterations in cancer cells are numerous and include aerobic glycolysis, reduced oxidative phosphorylation and ... turns glycolysis into an ATP-consuming process. Targeting aldolase ...

These cristae house the electron transport chain complexes (Complexes I to IV) and ATP synthase (Complex V), which are essential for oxidative phosphorylation. The matrix contains citric acid cycle ...

RNA-seq and MS analyses indicated that L-arginine switched glycolysis to oxidative phosphorylation in inflammatory osteoclasts leading to increased ATP production, purine metabolism and elevated ...

which resulted in downregulation of ATP-dependent pathways, and activation of cGAS-STING signaling. However, OPAI subtype was marked with active mitochondrial oxidative phosphorylation (OXPHOS), ...

This results in ATP production through the oxidative phosphorylation system via the mitochondrial respiratory chain. Persons with long-chain fatty acid pathway defects such as ...

Cyanobacteria began contributing oxygen to Earth's mostly noxious atmosphere more than 2 billion years ago. The photosystem ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

You will be redirected to our submission process. Oxidative stress, an imbalance between the production of reactive oxygen ...