Cardiovascular diseases account for approximately 30% of deaths worldwide and remain a leading cause of morbidity and ...

BACKGROUND: Classically, hypertrophic cardiomyopathy (HCM) has been viewed as a single-gene (monogenic) disease caused by ...

Background: In severely symptomatic patients with obstructive hypertrophic cardiomyopathy (HCM), VALOR-HCM trial (Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are ...

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Almost everyone who first sees moving heart walls, valves, and flows by echocardiography experiences fascination and wonder. Echocardiography is unique among cardiac imaging modalities because It ...

Cardiac electrophysiology (EP) is a relatively young field. The first surgical ablation of an accessory pathway and the first ...

The EF-hand Ca 2+ sensor protein S100A1 has been identified as a molecular regulator and enhancer of cardiac performance. The ability of S100A1 to recognize and modulate the activity of targets such ...

Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate of ≈0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart failure has ...

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Kawasaki disease (KD), an acute self-limited febrile illness that primarily affects children <5 years old, is the leading cause of acquired heart disease in developed countries, with the potential of ...

Co–first author and co-chair. Circulation is available at www.ahajournals.org/journal/circ The American Heart Association makes every effort to avoid any actual or ...