Are there therapies to slow the decline in lung function that occurs in patients with bronchiectasis? Bronchiectasis is a progressive disease, and frequent exacerbations are critical events ...

Treatment with fidanacogene elaparvovec, a recombinant adeno-associated virus (AAV) vector developed for the treatment of hemophilia B, led to sustained expression of the high-activity factor IX ...

Tecovirimat is available for the treatment of mpox (formerly known as monkeypox) in Europe and the United States, on the basis of findings from efficacy studies in animals and safety evaluations ...

Atrial fibrillation is the most common cardiac arrhythmia that is encountered in clinical practice, with some 4.5% of the general population affected in the United States. It has been nearly 30 ...

A 79-year-old woman was evaluated for cough and weight loss. Chest imaging and thoracentesis findings confirmed the presence of an exudative right pleural effusion. A diagnosis was made.

In the initial months of the Trump administration, numerous executive orders have led to a chaotic dismantling of U.S. foreign-assistance and global health efforts. These orders have already had ...

During the American Revolution, more than in any subsequent U.S. war, doctors played critical roles beyond their medical functions. A key leader at the outset of the war was Dr. Joseph Warren.

The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...