Bilirubin, a by-product of haem metabolism, plays a crucial role in human physiology beyond its well-known association with jaundice. Emerging evidence underscores its antioxidant and cell ...

The metabolism of bilirubin begins with its production from heme in the spleen and bone marrow, followed by transportation to the liver, where it undergoes enzymatic conversion.

CONGENITAL defects in bilirubin metabolism are a relatively infrequent cause of jaundice. ... Disorders of Bilirubin Metabolism, The Liver, (229-244), (2020) ...

Two recent observations linking these phenobarbital-induced changes in the liver with modifications of bilirubin metabolism have caught the fancy of hepatologists.

Excessive and often lethal blood levels of bilirubin can result from mutations in a single gene that are the cause of the metabolic disease known as Crigler-Najjar syndrome type 1 (CNS1). A new ...

The research team was able to identify that the gene variant can be linked to an increase in another enzyme, UGT1A1, that is important for the body's metabolism of bilirubin.

(HealthDay News) — Low serum total bilirubin levels may improve risk prediction of coronary artery disease (CAD) in patients with metabolic syndrome, according to research published in the ...