Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

Technical Report Published: March 2000 Custom fluorescent-nucleotide synthesis as an alternative method for nucleic acid labeling Octavian Henegariu, Patricia Bray-Ward & David C. Ward Nature ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

Every living cell must interpret its genetic code — a sequence of chemical letters that governs countless cellular functions.

A large-scale Mendelian randomization study found no genetic evidence that vitamins A, C, or D reduce the risk of major ...

Cyclic adenosine 3’,5’-monophosphate (cAMP) is a versatile secondary messenger that communicates with Guanine Nucleotide Exchange Factor (EPAC) to transfer cellular signaling and regulates numerous ...

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

Alignment and sequencing errors are a major concern in molecular evolution, and this valuable study represents a welcome improvement for genome-wide scans of positive selection. This new method seems ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) linked to colorectal cancer (CRC) risk in European and Asian populations, but studies in admixed ...

The paper summarizes a proposed role for error-coding in shaping the composition of the natural nucleotide alphabet. It is argued that as nucleotide replication is essentially an information ...