Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic ...

These cells came from a person with Gitelman-like syndrome, a disorder linked to mitochondrial dysfunction. The correction ...

Cytosine is one of the four main nitrogenous bases found in DNA and RNA, along with adenine (A), guanine (G), and thymine (T) or uracil (U). It is a pyrimidine derivative, meaning it has a single-ring ...

Using a 3D human skin model, they showed that C boosts thickness in the epidermal skin layer by activating genes linked to ...

Effect of cytosine modifications on DNA flexibility. The DNA cyclization assay was introduced by Shore et al. 37 as a measure of the DNA’s mechanical properties. Here we used a single-molecule ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations ...

Males imprint their DNA by adding methyl modifications to it in a way that alters the activity of genes in order to promote ...

Moving toward clinical development, the researchers demonstrated efficient delivery of mRNA mitochondrial base editors using ...

RNA shares Adenine (A), Guanine (G) and Cytosine (C) with DNA, but contains Uracil (U) rather than Thymine. Base Pairs: Adenine and Thymine pair (A-T) Cytosine and Guanine pair (C-G) Adenine and ...

Our genomic DNA is comprised of four bases—cytosine (C), thymine (T), guanine (G) and adenosine (A). These bases join together into approximately 3 billion different base pairs, arranged in a ...

Challenges of Treating DNA with Bisulfite. Incomplete bisulfite treatment is a major challenge in methylation detection methods. Bisulfite conversion relies on the chemical modification of cytosine in ...

Thymine (T) is one of the four nucleobases found in DNA, alongside adenine (A), guanine (G), and cytosine (C). It is a pyrimidine derivative, meaning it has a single-ring structure. Thymine plays a ...