Equity Insider News Commentary Issued on behalf of Oncolytics Biotech Inc. VANCOUVER, BC, June 24, 2025 /PRNewswire/ ...

Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...

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Background: Dentin phosphoprotein (DPP) is the most abundant non-collagenous protein in dentin, which is highly phosphorylated and plays key roles in dentin biomineralisation. The aetiology of ...

RIZ also appears to play an important role in hereditary tumors of the MIN pathway as suggested by the frequent frameshift mutations in HNPCC tumors (15). The mutations are located at two ...

Comprehensive gene analysis using next-generation sequencing revealed a novel heterozygous frameshift pathogenic variant (c.1366delG, p.Ala456ProfsTer75) in the GCM2 gene (NM_004752.4). Sanger ...

An example of this relates to the gene, TCTN3, whereby patients with bilallelic nonsense/frameshift mutations have Meckel syndrome – which is prenatally lethal – whereas a p.Gly314Arg missense ...

Mutations in the gene for fibrillin-1 ( FBN1 ) have been shown to cause Marfan syndrome, an autosomal dominant disorder of connective tissue characterised by pleiotropic manifestations involving ...