Nanopores are under investigation for single-molecule DNA sequencing. The α-hemolysin (αHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual ...

Pseudoisocytosine (J), a neutral analogue of protonated cytosine, is currently the gold standard modified nucleobase in peptide nucleic acids (PNAs) for the formation of J·G-C triplets that are stable ...