The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

San Francisco 49ers head coach Kyle Shanahan confirmed Wednesday that the team discussed the possibility of signing ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

Head coach Kyle Shanahan and defensive coordinator Nick Sorensen broke down the team's performance against the Green Bay ...

San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team ...

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay ...

Sunday, 8:20 p.m. EST, NBC BetMGM NFL odds: Bills by 7. Series record: Bills lead 7-6. Against the spread: 49ers 4-7, ...

Kyle Shanahan was asked about 49ers quarterback Brock Purdy's injured throwing shoulder on Monday. Here's what Shanahan said ...

Brandon Allen's first start with the 49ers didn't go so well. He made some nice throws, but he fumbled twice, threw an ...

San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because ...

San Francisco 49ers head coach Kyle Shanahan told reporters that quarterback Brock Purdy did some light throwing without any ...