The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The 49ers won't have their best pass rusher when they face the Bills on Sunday. Nick Bosa will miss his second game in a row with an oblique injury ...

The San Francisco 49ers are on the verge of falling out of contention for a playoff spot in the NFC after consecutive losses ...

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

Matt Maiocco shares the latest practice report for the San Francisco 49ers and Buffalo Bills ahead of their Week 13 game on ...

Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

The San Francisco 49ers received important Brock Purdy, Trent Williams and Nick Bosa injury updates on Wednesday.

San Francisco 49ers defensive end Nick Bosa (hip/oblique) was pulled from his team's Week 11 loss to the Seattle Seahawks due ...