Clinical data standards aim to identify, define, and standardize data elements relevant to clinical topics in cardiovascular medicine, with the primary goal of assisting data collection and use by ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a high incidence of indeterminate left ventricular (LV) filling pressure. We ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Cardiac arrest is common and deadly, affecting up to 700 000 people in the United States annually. Advanced cardiac life support measures are commonly used to improve outcomes. This “2023 American ...

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...

Hematoma expansion is associated with worse ICH outcome. There is now a range of neuroimaging markers that, along with clinical markers such as time since stroke onset and use of antithrombotic agents ...

Perioperative stroke is a severe surgical complication associated with substantial morbidity, disability, and mortality. It is defined as a stroke occurring during surgery or within 30 days ...

Among patients with diabetes, patients who delayed statin therapy had a significantly higher cardiovascular risk; this relationship was mediated by higher low‐density lipoprotein cholesterol levels.

Low‐density lipoprotein cholesterol (LDL‐C) is a major causal factor in the pathophysiology of atherosclerotic cardiovascular disease (ASCVD). 1 Epidemiological studies have consistently demonstrated ...

In this study, we screened out the unique heart-enriched and stress-overload–responded circCDYL from a substantial RNA-seq of cardiac circular RNAs, which is strongly correlated with pathological ...

Cardiac rehabilitation (CR) reduces mortality rates and improves the quality of life of patients with cardiovascular disease (CVD), 1 and its use is supported by American College of ...

The effect of these interrelated, sometimes competing and sometimes complementary, trends on clinical practice in the United States has not been clearly defined. In this issue of the Journal, Stehlik ...