“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...

Strapped with an extra APP, people with Down’s syndrome are all but destined to develop Alzheimer’s dementia if they live ...

Brain age gap (BAG) is a useful metric because it predicts one’s age-adjusted vulnerability to a range of neurological disorders, such as AD, dementia, and stroke. Although brain age may indeed ...

Damaged neurons leak proteins into bodily fluids, creating potential markers for neurodegenerative diseases including Alzheimer's. But one such prospect might be less clear-cut a measure of AD ...

How do astrocytes react to Alzheimer’s disease pathology? It’s complicated, according to the largest single-nuclei RNA-Seq study of these cells published thus far. Scientists led by Sudeshna Das at ...

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Application budgets are limited to $400,000 direct costs per year. The maximum project period is 3 years.

Application budgets are capped at $1 million in direct costs per year. The maximum project period is 5 years.

The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year. June 02, 2025 (Letter of Intent due May 1, 2025 ...